李单

发布时间:2023.03.10 10:46


姓名:李单

出生年月:19834

学位:博士

职称、职位:副教授、硕士生导师

Emailshaoweitie@163.com

教育经历

2010/09-2014/12,永利集团88304官网,材料学,博士;

2006/09-2009/12,北京化工大学,化学工程,硕士;

2002/09-2006/12,中国石油大学,化学工程,学士。

工作经历

2015/1-至今,永利集团88304官网,永利集团88304官网化工系,副教授

2009/9-2010/9,永利集团88304官网,化学工程学院化工系,助教

科研概况

科研工作方面,主要从事功能材料和生物医用材料等领域的交叉研究。目前,已发表SCI论文多篇,包括Chemistry-An Asian JournalColloids and Surfaces B: BiointerfacesNew Journal of ChemistryCarbohydrate PolymersInternational Journal of Pharmaceutics等国际知名期刊。主持企业横向项目多项,参与包括国家重点研发计划、国家自然科学基金、国家工信部重大专项在内的国家级、省部级重大和重点科技项目近20项,获湖北省科技进步二等奖1项。

研究领域

1)功能精细化学品的研制;

2)天然高分子衍生及其纳米体系的构建;

3)生物药用材料及其制备新技术。

科研项目

(1) 202120HX03JPPT66万元,主持;

(2) 8-甲基葵醛的合成研究,10万元,主持;

(3)丁羟推进剂化学降解剂应用及AP回收提取技术研究,JPPT,50万元,主持;

(4) JPPT-135-X-899JPPT470万,参与;

(5)JPPT-135-X-067JPPT365万,参与;

(6)JPPT-135-X-066JPPT 643万,参与;

(7)201520PT02JPPT 164.25万元,参与;

(8)选择性吸附烯烃材料的构建与稳定化(2022YFB3806800), 国家重点研发计划,1000万元,参与。

代表论文

1Li Dan, Lu Bo, Zhang Hong, Huang Zhijun, Xu Peihu, Zheng Hua*, Yin Yihua, Xu Haixing, Liu Xia, Lou Yiceng, Zhang Xueqiong, Xiong Fuliang, Synthesis and in vitro Evaluation of Methotrexate Conjugated O, N-carboxymethyl Chitosan via Peptidyl Spacers, Journal of nanoparticle research ,2014, 16: 2609, SCI, IF2.101.

2Li Dan, Lu Bo, Zhang Hong, Huang Zhijun, Xu Peihu, Zheng Hua*, Yin Yihua, Xu Haixing, Liu Xia, Lou Yiceng, Zhang Xueqiong, Xiong Fuliang, A novel melphalan polymeric prodrug: Preparation and property study, Carbohydrate Polymers, 111 (2014) 928–935, SCI, IF4.219.

3Mengheng Lei; Gang Chen; Mengyao Zhang; Jiaqing Lei; Tingting Li; Dan Li; Hua Zheng; A pH-sensitive drug delivery system based on hyaluronic acid co-deliver doxorubicin and aminoferrocene for the combined application of chemotherapy and chemodynamic therapy, Colloids and Surfaces B: Biointerfaces, 2021, 203, 111750.

4Multifunctional Pd/MOFs@MOFs Confined Core-Shell Catalysts with Wrinkled Surface for Selective Catalysis, Chem Asian J. 2021, 16, 1-6.

5Degradation of Disposal Hydroxyl-Terminated Polybutadiene Composite Solid Propellant, Wuhan University Journal of Natural Sciences, 2020, Vol.25 No.3.

6All-around coating of CoNi nanoalloy using a hierarchically porous carbon derived from bimetallic MOFs for highly efficient hydrolytic dehydrogenation of ammonia-boraneNew Journal of Chemistry2020, 44 3021-3027.

7Isolation and Characterization of Acid-soluble Collagen and Pepsin-soluble Collagen from the Skin of Hybrid SturgeonJournal of Wuhan University of Technology-Mater. Sci. Ed.201934(4) 950-959.

8Jianhong Liao, Haoran Zheng, Rui Hu Jun Cao, XuanWei, Dan Li,Hua Zheng, and Yihua YinHyaluronan Based Tumor-Targeting and pH-Responsive Shell Cross-Linkable Nanoparticles for the Controlled Release of DoxorubicinJournal of Biomedical Nanotechnology2018141-14.

9Ziqie Rao, Hongyu Ge, Liangling Liu, Chen Zhu, Lian Min, Meng Liu, Lihong Fan, Dan LiCarboxymethyl cellulose modified graphene oxide as pH-sensitive drug delivery systemInternational Journal of Biological Macromolecules 2018 (107) 1184-1192.

10Jun Cao, Haoran Zheng, Rui Hu, Jianhong Liao, Zengming Fei, Xuan Wei, Xiong Xiong, Fanglin Zhang, Hua Zheng, and Dan Li. pH-Responsive Nanoparticles Based on Covalently Grafted Conjugates of Carboxymethyl Chitosan and Daunorubicin for the Delivery of Anti-Cancer Drugs[J]. Journal of Biomedical Nanotechnology, 2017, 13(12): 1647-1659.

11 Hu Zhengyu, Zheng Hua, Li Dan, Xiong Xiong, Tan Mingyuan, Huang Dan, Guo Xing, Zhang Xueqiong, Yan Han, Self-assembled nanoparticles based on folic acid modified carboxymethyl chitosan conjugated with targeting antibody, Journal of Wuhan University of Technology-materials science edition, 2016, 31, 446-453.


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